立藤美学园，仅仅因为一个入侵者——“它们”，而化作了地狱的坩埚！“它们”袭击人，咬人，产生出新的“它们”席卷了整个学园。在化成恶魔的世界的学园内，小室孝和青梅竹马宫本丽、朋友井豪永，暂时去避难。但是，为了保护丽而被“它们”咬的永却变成了“它们”……剩下来的两人，与其他幸存者，同级同学高城沙耶、平野户田、剑道部主将毒岛冴子、校医鞠川静香汇合，下定决心逃出学园！他们有办法活下来吗！？
The series follows the ups and downs of third-generation restaurateur BOB (H. Jon Benjamin), who runs Bob's Burgers with the help of his wife and their three kids. Bob and his unpredictable family have big ideas about burgers, but they fall short on service and sophistication. Despite their restaurant's greasy counters, lousy location and dearth of customers, Bob and his family are determined to make every "Grand Re-Re-Re-opening" a success.
