被孤儿院赶出、濒临饿死边缘的少年中岛敦与一群风格奇异的男人们相遇了。
平凡的高一学生陆水银，喜欢校内第一的大小姐陆怜。 但陆怜突然不可思议地被诱拐到盗墓游戏的世界中， 追着她的水银也在美少女向导双子星的邀请下前往那个世界。 之后，他接过已被加以百亿课金的终端。 水银为了守护陆怜，成为游戏世界最后的“守墓人”，参加与“盗墓者”之间的攻防战。 在战斗的途中，他们的秘密也逐渐揭晓——。
转生到乙女游戏世界成为圣女（女主角）的赛蕾丝蒂。她的使命是与各路美男子相恋，并携手击败魔王。然而，由于赛蕾丝蒂是个从未玩过乙女游戏的门外汉，命运的齿轮开始错位！这个只对女仆工作感兴趣的少女彻底无视游戏剧情，无意识地将圣女魔法全用在女仆工作上。她唯一的目标就是成为 No.1 女仆。最终为了理想的工作、为了主人，她不仅颠覆了女仆常识，更将改变整个世界。这个因魔王降临而战栗的世界将会如何？看自称普通少女如何摧毁乙女游戏剧本的误会系奇幻喜剧！
In the year 1524, the former Assassin Ezio Auditore retired to a villa in the countryside of Tuscany, with his wife Sofia and children Marcello and Flavia. While Ezio wrote in his study, Sofia asked him to watch Flavia while she and Marcello visit his sister Claudia. Shortly after, he left his study to tend their vineyards while Flavia played nearby the villa. In the midst of his harvest, he saw a stranger cloaked in black, talking to Flavia. Fearing the worst, Ezio hurriedly intercepted the stranger, though Flavia told him that she was no danger, as Ezio saw her necklace with the Assassin insignia...
